SAFE Fertility Group PCL (SFC Clinic): 20 Years of Advancing IVF and ICSI Technology in Thailand
In the field of fertility treatment, ICSI and IVF, SAFE Fertility Group PCL (SFC Clinic) is far more than a medical center providing assisted reproductive services. It has established itself as a trendsetter and benchmark in fertility care, helping elevate industry standards and drive technological innovation both nationally and regionally.
Two Decades of Driving Fertility Care Through Spearheading Advanced Reproductive Technology and International Fertility Standards
As SAFE Fertility Group PCL (SFC Clinic) enters its 20th year, it marks another significant milestone while continuing its strategic expansion plans. The Group currently operates five clinic branches across Thailand—Gaysorn Amarin (Headquarter), Ramindra, Sriracha, Khon Kaen, and Phuket—extending comprehensive fertility care to both domestic and international patients. Each equipped with its own in-house embryology laboratory. The Group also operates NGG Thailand, a subsidiary that extends its laboratory expertise to the broader reproductive medicine sector."
Founded by Wiwat Quangkananurug, M.D., The Founder and CEO of SAFE Fertility Group PCL. has played a pivotal role in transforming Thailand’s fertility treatment landscape over the past two decades.
“20 years ago, my starting point was simple—I wanted to give every patient who walked through our doors the best possible chance. That meant holding ourselves to the highest international standards from day one, whether it was the people we trained, the technology we invested in, or the protocols we built. That commitment hasn’t changed.”
Setting Clinical Benchmarks with International RTAC Accreditation
One of its most notable achievements was becoming the first fertility clinic in Thailand to obtain RTAC (Reproductive Technology Accreditation Committee) certification from Australia and New Zealand. Prior to this, ICSI/IVF standards in Thailand largely depended on the protocols of individual hospitals. SAFE’s achievement effectively established a new benchmark for reproductive medicine in the country.
The RTAC accreditation not only elevated industry standards but also encouraged fertility clinics to improve their laboratory systems and patient care processes to meet international standards, ultimately enhancing patient safety across the sector.
In-House Embryology Laboratories and PGTseq Technology
SAFE Fertility Group PCL (SFC Clinic) has consistently invested in advanced reproductive technologies through its own in-house embryology laboratory, NGG Thailand, offering PGTseq exclusively—an embryo chromosomal screening technology that combines Targeted Next-Generation Sequencing (NGS) with Single Nucleotide Polymorphisms (SNP) analysis that provides detailed 3-Mb resolution. These innovations help improve treatment success rates while providing more accurate detection of genetic abnormalities.
NGG Thailand's laboratory infrastructure extends beyond SAFE's own branches, providing embryology laboratory services to clinic and hospital partners within the reproductive medicine sector, further extending the Group's in-house expertise across a wider network of care.
“Having our own laboratory means we maintain direct oversight over the core processes that matter most — the environment, the timing, the protocols. When something needs adjusting, we can act immediately. And because our standards are built to align with international accreditation, that level of control isn't just internal practice — it's externally verified.”
— Sujin Chanchamroen, Chief Laboratory Officer, SAFE Fertility Group PCL
Personalized 1-on-1 Patient Care Throughout the ICSI and IVF Journey
The clinic also differentiates itself through its personalized 1-on-1 patient care model, supported by dedicated Personal Assistants who guide patients throughout every stage of the treatment journey—from initial consultation to the completion of their fertility program.
“After nearly 20 years of supporting patients through ICSI/IVF, we realise your fertility treatment can be an emotional roller coaster! We have been with our patients on their happiest moments through to their most difficult moments. Our role goes far beyond the day-to-day coordination of treatments. It’s about being there, to listen, to hold your hands, to reassure, and make sure no one feels alone. With our highly experienced, multilingual team by your side, we strive each day to make every step of your journey simple, comfortable, and stress free - from your first consultation to the final step of your treatment, we are there! Not because it’s our job – simply because we care with our hearts and want to see each of our patients succeed!”
— Warosinee Chaiwon, Personal Assistant Manager, SAFE Fertility Group PCL
Addressing Delayed Parenthood and Modern Family Planning Needs
These developments align with significant global demographic shifts, including declining birth rates, delayed parenthood, and increasing expectations among prospective parents to have healthy children from birth. Today, many couples choose to prioritize career development, financial stability, and personal readiness before starting a family.
As a result, many individuals attempt pregnancy at an age when fertility levels and egg quality have already begun to decline, often beyond the peak reproductive years.
Consequently, ICSI/IVF is no longer viewed solely as a solution for infertility. It has evolved into a critical reproductive technology that supports safer pregnancies and improves health outcomes for both mothers and babies.
This trend is reflected in the continuing decline in global birth rates over recent decades. In many countries, the Total Fertility Rate (TFR) has fallen below the population replacement level of approximately 2.1 children per woman, highlighting a growing gap between the desire to have children and the ability to conceive naturally.
Modern parenthood is therefore no longer defined simply by achieving pregnancy. Increasingly, it encompasses the goal of having a healthy child from birth, with greater emphasis placed on embryo quality, genetic health, and the reduction of medical risks from the earliest stages of life.
“Fertility is deeply personal — and so is the decision of what to do about it. When I assess egg quality and embryo health together, what I'm building is a personalized picture that belongs to that specific patient. My first conversation with anyone who comes in is never about treatment. It's about understanding where they actually are, so we can figure out together what makes sense for them.”
Thailand’s Growing Role as a Hub for Fertility Treatment and Medical Tourism
Despite declining birth rates, Thailand’s fertility treatment market continues to expand. Industry estimates suggest that the market could reach approximately THB 6.3 billion, with annual growth of around 5–6%.
While many modern couples may find it more challenging to conceive, those who decide to have children are increasingly willing to invest in the best available treatment options. Average spending per case has risen significantly, driven by the adoption of advanced genetic screening technologies such as Preimplantation Genetic Testing (PGT), which can detect chromosomal abnormalities—including conditions such as Down syndrome—and support more informed decision-making before embryo transfer.
Importantly, Thailand has emerged as a leading destination for fertility tourism. Beyond serving local patients, the country has become one of the world's preferred destinations for international couples—particularly from China, India, and other ASEAN countries—seeking advanced fertility treatment. SAFE Fertility Clinic has positioned itself to serve this growing segment, supporting international patients through every stage of treatment, including coordination across its split-cycle protocols for those traveling between countries.
Choosing a fertility clinic is one of the most important decisions a family can make. Patients expect their investment to deliver the highest possible chance of success while maintaining the highest standards of safety.
This principle reflects SAFE’s own journey over the past two decades. Growing alongside the evolution of global IVF technology, the organization remains committed to advancing industry standards and maintaining its position as a leader in reproductive medicine and fertility innovation, both in Thailand and on the international stage.
SAFE Fertility Group PCL is a Thailand fertility care provider operating five branches—Gaysorn Amarin (Flagship), Ramindra, Sriracha, Khon Kaen, and Phuket. Founded in 2007, SAFE was the first fertility clinic in Thailand to receive RTAC accreditation and continues to invest in advanced reproductive technologies, including its in-house embryology laboratory operated through subsidiary NGG Thailand.